You can execute the Testmate scripts from VBScript in the same way as it is run using command line. Copy the following code in a .vbs file and run it. VBScript 1 2 3 4 5 'Create Shell Object using vbscript Set obj = CreateObject("Wscript.Shell")   'Run the shell command with parameters obj.Run """C:\<strong>Testmate¬†</strong>\TesterAt.exe""¬† ¬†